Red Spot, which was discontinued in the mid-1960s, rejoins Green Spot and Yellow Spot in Irish Distillers' Spot Whiskeys range.
The team at Midleton Distillery, where the Spot Whiskeys are produced, "worked closely" with the Mitchell family to bring Red Spot back to market.
The reimagined Red Spot is a triple-distilled, single pot still Irish whiskey that has been matured for a minimum of 15 years in a combination of casks pre-seasoned with Bourbon, oloroso Sherry and Marsala fortified wine.
Kevin O'Gorman, master of maturation at Midleton Distillery, said the distillery "looks forward to one day completing the full Spot Whiskeys range", suggesting the last discontinued expression Blue Spot is also set to return.
The Spot Whiskeys range derives its name from the Mitchell's practice of marking their maturing casks of whiskey with a spot of coloured paint to determine the age potential of the liquid.
Jonathan Mitchell, managing director at Mitchell & Son, said: "It has been fascinating to work with Kevin O'Gorman and the craftsmen at Midleton Distillery to recreate Red Spot and a real journey into the rich history of our family and its role in Dublin's whiskey bonding era.